根据耶鲁大学癌症研究中心的一项研究称，在部分乳房切除术中只需10分钟的手术便可切除多余的乳房组织，这不但可以免去成千上万的乳腺癌患者进行第二次手术，也降低了每位病人高达750美元的花费成本。
该研究结果将在2015年12月10日年度圣安东尼奥乳腺癌研讨会中发布。
在美国约近300，000名妇女被诊断为乳腺癌，每年超过半数乳腺癌患者为了保乳通过部分乳房切除手术来祛除疾病。大约三分之一经历过这个过程的病人都有较广的肿瘤边界，或者在移除组织的边界发现有肿瘤细胞，所以需要第二次手术以确保没有病灶的存留。耶鲁大学的一项研究表明，初次手术中在肿瘤部位周围去除多余组织被称为“术后腔内边界刮除术” (CSM)——这样就会减少近一半的二次手术。
考虑到这些数据，耶鲁大学研究人员研究这种技术如何在只增加10分钟手术时间的情况下来完成手术从而降低成本。
“在一段时期内医疗成本迅猛飞涨，患者的治疗需要面临巨大的医疗费用负担，这对癌症治疗的价值越来越重要。”耶鲁医学院Anees Chagpar博士说， “我们发现“术后腔内边界刮除术”使得很少患者再次回到手术室，不造成额外成本的增加。显然，这是一个对所有人都有利的结果包括病人，医生和支付者。”
耶鲁大学的研究促使世界各地的外科医生对CSM的益处的讨论。这种技术现在已经被纳入一些专业组织的指导方针，一个多中心研究验证耶鲁大学的发现始于2016年。
A 10-minute procedure to remove a little more tissue during a partial mastectomy could spare thousands of breast cancer patients a second surgery but and also cut costs by as much as $750 per patient, according to a Yale Cancer Center study. The findings are scheduled for presentation Dec. 10 at the 2015 Annual San Antonio Breast Cancer Symposium. Nearly 300,000 women in the United States are diagnosed with breast cancer each year; more than half undergo breast-conserving surgery with a partial mastectomy to remove the disease. about a third of patients who undergo this procedure have "positive margins," or cancer cells found at the edge of the removed tissue, and will require a second surgery to ensure that no cancer remains. A Yale study, published online in May in the New England Journal of Medicine, demonstrated that removing more tissue all the way around the tumor site during the initial surgery—known as cavity shave margins (CSM)—could cut the need for a second surgery in half. Given these data, the Yale investigators explored how this technique, which adds only 10 minutes to the operation time, would affect costs. "At a time when healthcare costs are skyrocketing, and patients face significant financial burden with their treatments, it's increasingly important to look at value in cancer care," said first author Dr. Anees Chagpar, associate professor of surgery (oncology) at Yale School of Medicine and director of The Breast Center at Smilow Cancer Hospital at Yale-New Haven. "We found that taking cavity shave margins resulted in fewer return trips to the operating room at no added cost. Clearly, this is a win all around—for patients, providers, and payers." The Yale study prompted discussion among surgeons around the world about the benefits of CSM. This technique has now been incorporated into some professional organizations' guidelines, and a multi-center study to validate the Yale findings is set to start in 2016.